徐州威格顿生物科技有限公司
威格顿生物
Weigedun Biotechnology
ST14 Rabbit pAb
规格信息
| 规格 | 货号 |
|---|---|
| 50ul | WGD-Z-2600015 |
| 100ul | WGD-Z-2600015 |
详细参数
| 别名 | Matriptase; Suppressor of tumorigenicity 14 protein; Membrane-type serine protease 1; MT-SP1; Prostamin; Serine protease 14; Serine protease TADG-15; Tumor-associated differentially-expressed gene 15 protein; ST14; PRSS14; SNC19; TADG15 |
| 基因名 | ST14 |
| UniProt ID | Q9Y5Y6 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB,IHC-P,ICC/IF,IP |
| 宿主 | Rabbit |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG |
| 克隆性 | Polyclonal Antibody |
| 分子量 | Calculated MW:95 kDa ;Observed MW: 95 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:500-1:1000; IHC-1:50-1:200; IF-1:50-1:200; IP-1:50-1:100 |
| 存储缓冲液 | Liquid in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Matriptase (also known as MT-SP1, ST14, prostamin and epithin in mouse) is a tumor-associated type II transmembrane serine protease that is highly expressed in many human cancer-derived cell lines and is implicated in extracellular matrix re-modeling, tumor growth, and metastasis. Matriptase performs pleiotropic functions in the development of the epidermis, hair follicles, and cellular immune system. Sphingosine 1-phosphate (S1P, SPP), present in serum-derived lipoproteins, activates matriptase while matriptase activates both urokinase-type plasminogen activator and hepatocyte growth factor (HGF). Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is a Kunitz-type serine protease inhibitor identified as a strong inhibitor of matriptase and HGF. |