| 别名 |
PDI; PDA2; PDIP; PDIR; PDIA2 |
| 基因名 |
PDIA2 |
| UniProt ID |
Q13087 |
| 反应种属 |
Human,Mouse,Rat |
| 应用 |
WB,FC |
| 宿主 |
Rabbit |
| 偶联物 |
Unconjugated |
| 修饰 |
Unmodified |
| 亚型 |
IgG |
| 克隆号 |
R05-8X-8 |
| 克隆性 |
Monoclonal Antibody |
| 分子量 |
Calculated MW: 58 kDa; Observed MW: 58 kDa |
| 纯化方式 |
Affinity Chromatography |
| 产品形式 |
Liquid |
| 推荐稀释比 |
WB-1:1000-1:5000; FC-1:50-1:100 |
| 存储缓冲液 |
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| 保存温度 |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 |
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels. |