徐州威格顿生物科技有限公司
威格顿生物
Weigedun Biotechnology
ADGRB1 Mouse mAb
规格信息
| 规格 | 货号 |
|---|---|
| 50ul | WGD-Z-2610964 |
| 100ul | WGD-Z-2610964 |
详细参数
| 别名 | Adhesion G protein-coupled receptor B1; Brain-specific angiogenesis inhibitor 1) [Cleaved into: Vasculostatin-40; Vstat40); Vasculostatin-120; Vstat120] |
| 基因名 | ADGRB1 |
| UniProt ID | O14514 |
| 反应种属 | Human,Mouse |
| 应用 | WB,ELISA |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG2b |
| 克隆号 | 6Y1-P6-T5 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 173 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:4000; ELISA-1:200 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Adhesion G protein-coupled receptor B1 (ADGRB1), also known as brain-specific angiogenesis inhibitor 1 (BAI1), is a receptor involved in various physiological processes, including angiogenesis, synaptogenesis, and macrophage function. Structurally, it features multiple thrombospondin type 1 repeats and a GAIN domain that facilitates autoproteolysis, crucial for its signaling functions. Mutations in ADGRB1 are linked to diseases such as lung cancer and neurological disorders, highlighting its role in tumor suppression and neural development. Additionally, ADGRB1 mediates the engulfment of apoptotic cells by binding to phosphatidylserine, showcasing its importance in immune responses. |