徐州威格顿生物科技有限公司
威格顿生物
Weigedun Biotechnology
LMNTD2 Mouse mAb
规格信息
| 规格 | 货号 |
|---|---|
| 50ul | WGD-Z-2611794 |
| 100ul | WGD-Z-2611794 |
详细参数
| 别名 | Lamin tail domain-containing protein 2 |
| 基因名 | LMNTD2 |
| UniProt ID | Q8IXW0 |
| 反应种属 | Human |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 2T3-G4-S8 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 70 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | IHC-1:100-1:200 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Lamin tail domain containing 2 (LMNTD2) is a protein predicted to function as a structural constituent of chromatin and a regulator of mRNA splicing via the spliceosome. It contains a characteristic lamin tail domain that enables the formation of coiled-coil structures and potential DNA binding, similar to lamina-associated polypeptide 2-like proteins that maintain the integrity of the nuclear envelope. LMNTD2 is thought to interact with lamin filaments to modulate nuclear architecture and gene expression. Expression analysis indicates tissue-specific distribution in the brain, testis, and prostate. While its precise biological roles remain under investigation, its structural motifs suggest a significant involvement in nuclear scaffold organization and genomic stability. |