徐州威格顿生物科技有限公司
威格顿生物
Weigedun Biotechnology
C12orf42 Mouse mAb
规格信息
| 规格 | 货号 |
|---|---|
| 50ul | WGD-Z-2611915 |
| 100ul | WGD-Z-2611915 |
详细参数
| 别名 | Uncharacterized protein C12orf42 |
| 基因名 | C12orf42 |
| UniProt ID | Q96LP6 |
| 反应种属 | Human |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 1M8-Q6-I9 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 39 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | IHC-1:100-1:200 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Chromosome 12 open reading frame 42 (C12orf42) encodes an uncharacterized protein that has been associated with cell cycle-dependent processes and mitotic structures in proteomic analyses. Although it may be expressed at low levels due to potential nonsense-mediated mRNA decay, it is recognized for its role in skin pigmentation. Clinical relevance is well-established through its association with rare genodermatoses, specifically Dyschromatosis Universalis Hereditaria and Dyschromatosis Symmetrica Hereditaria. These conditions are characterized by hyper- and hypopigmented macules, often presenting in infancy or childhood with symmetric or widespread distribution, primarily affecting individuals of East Asian descent. |