徐州威格顿生物科技有限公司
威格顿生物
Weigedun Biotechnology
PPP1R9B Mouse mAb
规格信息
| 规格 | 货号 |
|---|---|
| 50ul | WGD-Z-2611931 |
| 100ul | WGD-Z-2611931 |
详细参数
| 别名 | Neurabin-2; Neurabin-II; Protein phosphatase 1 regulatory subunit 9B; Spinophilin |
| 基因名 | PPP1R9B |
| UniProt ID | Q96SB3 |
| 反应种属 | Human,Rat |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 9G6-Q4-C9 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 89 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Neurabin-2 (PPP1R9B) is a protein that belongs to the neurabin family and is characterized by its role in linking the actin cytoskeleton to various signaling pathways. It contains an F-actin-binding domain and a PDZ domain, allowing it to interact with multiple proteins and facilitate cellular processes such as synaptic signaling and cell adhesion. Neurabin-2 is predominantly expressed in the brain, where it plays a critical role in the organization of the postsynaptic density, thereby influencing synaptic plasticity and neuronal communication. Dysregulation of neurabin-2 has been implicated in several neurological disorders, including schizophrenia and autism spectrum disorders, where altered synaptic function may contribute to disease pathology. Additionally, its involvement in cancer progression has been noted, as changes in neurabin-2 expression can affect tumor cell migration and invasion. |