Overview
| 别名 | HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8 |
| 基因名 | HDAC8 |
| UniProt ID | Q9BY41 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB,FC,IP |
| 宿主 | Rabbit |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG |
| 克隆号 | R07-7W-4 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 42 kDa; Observed MW: 42 kDa |
| 纯化方式 | Affinity Chromatography |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000-1:5000; FC-1:50-1:100; IP-1:20-1:50 |
| 存储缓冲液 | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility. |
检测原理