Overview
| 别名 | Deubiquitinating enzyme 10; UBPO; USP10; KIAA0190; MGC124997; |
| 基因名 | USP10 |
| UniProt ID | Q14694 |
| 反应种属 | Human |
| 应用 | WB,IHC-P,ICC/IF,IP |
| 宿主 | Rabbit |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG |
| 克隆号 | R04-3K-3 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 87 kDa; Observed MW: 110 kDa |
| 纯化方式 | Affinity Chromatography |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000-1:5000; IHC-P-1:200-1:500; ICC/IF-1:200-1:500; IP-1:10-1:100 |
| 存储缓冲液 | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. |
检测原理