Overview
| 别名 | Antigen NY-CO-13; Cellular tumor antigen p53; Phosphoprotein p53; TP53; Tumor suppressor p53 |
| 基因名 | TP53 |
| UniProt ID | P04637 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB,ICC/IF,FC,IP |
| 宿主 | Rabbit |
| 偶联物 | Unconjugated |
| 修饰 | Acetylated |
| 亚型 | IgG |
| 克隆号 | R01-6U-1 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 44 kDa; Observed MW: 53 kDa |
| 纯化方式 | Affinity Chromatography |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:500-1:1000; IF-1:50-1:200; IP-1:20 |
| 存储缓冲液 | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. |
检测原理