Overview
| 别名 | CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91 |
| 基因名 | STAT1 |
| UniProt ID | P42224 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB,IHC-P |
| 宿主 | Rabbit |
| 偶联物 | Unconjugated |
| 修饰 | Phosphorylated |
| 亚型 | IgG |
| 克隆号 | R03-7N-3 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 87 kDa; Observed MW: 87 kDa |
| 纯化方式 | Affinity Chromatography |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000-1:5000; IHC-P-1:100-1:200 |
| 存储缓冲液 | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C. |
检测原理