Overview
| 别名 | RAF1; RAF; RAF proto-oncogene serine/threonine-protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1 |
| 基因名 | RAF1 |
| UniProt ID | P04049 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB,IHC-P |
| 宿主 | Rabbit |
| 偶联物 | Unconjugated |
| 修饰 | Phosphorylated |
| 亚型 | IgG |
| 克隆号 | R03-2C-7 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 73 kDa; Observed MW: 73 kDa |
| 纯化方式 | Affinity Chromatography |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000-1:5000 |
| 存储缓冲液 | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. |
检测原理