Overview
| 别名 | SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src |
| 基因名 | SRC |
| UniProt ID | P12931 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB,FC |
| 宿主 | Rabbit |
| 偶联物 | Unconjugated |
| 修饰 | Phosphorylated |
| 亚型 | IgG |
| 克隆号 | R01-7N-7 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 60 kDa; Observed MW: 60 kDa |
| 纯化方式 | Affinity Chromatography |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000-1:5000; FC-1:50-1:100 |
| 存储缓冲液 | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2). |
检测原理