![[KD]Menin Rabbit mAb-抗体-威格顿生物](/uploads/20260414/ad4291519985458ac81d7dea66c4005d.png)
![[KD]Menin Rabbit mAb](/assets/addons/ldcms/ldcms2025/images/product-default-flat.png)
Overview
| 别名 | MEN1; SCG2; Menin |
| 基因名 | MEN1 |
| UniProt ID | O00255 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB,IHC-P,ICC/IF,IP |
| 宿主 | Rabbit |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG |
| 克隆号 | R05-4H-5 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 68 kDa; Observed MW: 68 kDa |
| 纯化方式 | Affinity Chromatography |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:500-1:1000; IHC-P-1:100-1:500; ICC/IF-1:20-1:50; IP-1:10-1:100 |
| 存储缓冲液 | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL)-containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes. |
检测原理