Overview
| 别名 | Maestro heat-like repeat-containing protein family member 2A; HEAT repeat-containing protein 7B1 |
| 基因名 | MROH2A |
| UniProt ID | A6NES4 |
| 反应种属 | Human |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 1G2-W7-W4 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 189 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Maestro heat like repeat family member 2A (MROH2A), also known as HEATR7B1, encodes a HEAT-domain-containing protein conserved across species. While its specific molecular function remains largely uncharacterized, the presence of HEAT repeats suggests a role in protein-protein interactions and intracellular transport. MROH2A is expressed in various tissues, including the brain, gastrointestinal tract, and reproductive organs. The gene is situated within a chromosomal region associated with 2q37 copy number variations. Clinically, MROH2A is implicated in Congenital Myasthenic Syndrome, a neuromuscular disorder characterized by impaired synaptic transmission and muscle weakness, suggesting a critical role for the protein in the maintenance or function of the neuromuscular junction. |
检测原理