Overview
| 别名 | EF-hand calcium-binding domain-containing protein 10 |
| 基因名 | EFCAB10 |
| UniProt ID | A6NFE3 |
| 反应种属 | Human,Mouse |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 9E8-E2-H9 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 14 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:2000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | EF-hand calcium binding domain 10 (EFCAB10) is a cytosolic protein characterized by multiple EF-hand motifs, structural domains that coordinate calcium ions in a pentagonal bipyramidal configuration. Functioning as a high-affinity calcium sensor, EFCAB10 likely undergoes conformational changes upon calcium binding to regulate downstream signaling targets. It localizes primarily to intracellular compartments, where it operates within calcium-dependent pathways. While direct monogenic disease associations are not extensively documented, the structural homology of its EF-hands to those in proteins like polycystin-2 suggests potential relevance to calcium signaling disorders and ciliopathies. |
检测原理