Overview
| 别名 | Fibroblast growth factor 18; FGF-18; zFGF5 |
| 基因名 | FGF18 |
| UniProt ID | O76093 |
| 反应种属 | Human |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 9S2-H6-C1 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 23 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | IHC-1:200-1:250 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Fibroblast growth factor 18 (FGF18) is a pleiotropic growth factor of the FGF8 subfamily that regulates cell proliferation, differentiation, and tissue repair. Signaling primarily through FGFR3c, FGF18 is a key regulator of chondrogenesis and cartilage maintenance. It also plays protective roles in the heart against hypertrophy and supports tissue homeostasis in the liver and intestine. FGF18 has significant therapeutic potential in regenerative medicine; recombinant forms have demonstrated efficacy in promoting cartilage repair and delaying osteoarthritis progression. Its safety profile and ability to mitigate tissue degeneration make it a promising candidate for treating degenerative joint and disc disorders. |
检测原理