Overview
| 别名 | Uncharacterized protein CXorf51B |
| 基因名 | CXorf51B |
| UniProt ID | P0DPH9 |
| 反应种属 | Human |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 1A8-L7-G3 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 12 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | IHC-1:200-1:250 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Chromosome X open reading frame 51B (CXorf51B) is a 108 amino acid human protein characterized as an intrinsically disordered protein (IDP) with an all-coil conformation under physiological conditions. Located at chromosomal position Xq27.3, it features a high content of basic residues, particularly lysine and arginine, alongside significant serine and threonine levels. These basic residue patches suggest a potential role in DNA or RNA binding. The protein is primarily expressed in the prostate and T-cells and is subject to post-translational regulation through phosphorylation at multiple consensus sites, including motifs for Calmodulin-Dependent Protein Kinase II and Protein Kinase A. While structural characterization has been performed using NMR spectroscopy, its specific biological functions and interaction partners remain largely uncharacterized, making it a target for functional de-orphanization studies. |
检测原理