Overview
| 别名 | Exocyst complex component 3-like protein 4 |
| 基因名 | EXOC3L4 |
| UniProt ID | Q17RC7 |
| 反应种属 | Human |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 6N3-Y4-Z6 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 79 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:2000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Exocyst complex component 3 like 4 (EXOC3L4) is a protein-coding gene that belongs to the SEC6 family and is predicted to be part of the exocyst complex. It plays a crucial role in targeting SLC2A4 vesicles to the plasma membrane in response to insulin in adipocytes, potentially directing vesicles to precise fusion sites. EXOC3L4 is involved in exocyst localization and exocytosis, and is predicted to enable SNARE binding activity. The protein consists of 722 amino acids and interacts with other exocyst complex components such as EXOC4, EXOC2, and EXOC7. Recent studies have associated rare variants in the splicing regulatory elements of EXOC3L4 with brain glucose metabolism in Alzheimer's disease, suggesting a potential link between EXOC3L4 splicing, vesicle transport, and AD-related phenotypes. |
检测原理