Overview
| 别名 | Putative heat shock protein HSP 90-alpha A4; Heat shock 90 kDa protein 1 alpha-like 2; Heat shock protein 90-alpha D; Heat shock protein 90Ad |
| 基因名 | HSP90AA4P |
| UniProt ID | Q58FG1 |
| 反应种属 | Human |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG2a |
| 克隆号 | 3A9-X9-X6 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 47 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Heat shock protein 90 alpha family class A member 4 (HSP90AA4P), a putative molecular chaperone with a length of 418 amino acids, predicted to promote the maturation, structural maintenance, and proper regulation of target proteins. It likely displays ATP binding and hydrolysis activities, unfolded protein binding, and contributes to cellular processes such as response to heat, protein folding, and stabilization. Predicted cytoplasmic localization suggests involvement in protein-containing complexes within neuronal cells and the perinuclear cytoplasmic region. As a member of the Hsp90 family, it shares similarities with functional Hsp90 isoforms, which are critical ATP-dependent chaperones facilitating the folding and stabilization of numerous client proteins under both normal and stress conditions. Dysregulation of Hsp90 chaperones is linked to cancer, neurodegenerative diseases, and infection, reflecting the broad clinical relevance of this protein family. |
检测原理