Overview
| 别名 | Integrator complex subunit 6-like; Protein DDX26B |
| 基因名 | INTS6L |
| UniProt ID | Q5JSJ4 |
| 反应种属 | Human,Mouse |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG2a |
| 克隆号 | 2D1-E3-R6 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 96 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Integrator complex subunit 6 like (INTS6L), also known as DDX26B, is a paralog of the Integrator subunit INTS6. It is associated with the Integrator complex, a multiprotein machinery that couples RNA polymerase II transcription with the processing of noncoding RNAs. Sharing homology with DEAD-box RNA helicases, INTS6L likely supports the scaffolding or regulatory functions of the complex, similar to INTS6, which aids in recruiting phosphatase modules. While its paralog INTS6 has established links to cancer as a tumor suppressor, specific disease associations for INTS6L remain less defined, though its structural conservation implies a contributory role in transcriptional regulation and RNA processing. |
检测原理