Overview
| 别名 | La-related protein 1B; La ribonucleoprotein domain family member 1B; La ribonucleoprotein domain family member 2; La-related protein 2 |
| 基因名 | LARP1B |
| UniProt ID | Q659C4 |
| 反应种属 | Human |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 6H2-B6-F6 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 105 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | IHC-1:200-1:250 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | La ribonucleoprotein 1B (LARP1B) is an RNA-binding protein characterized by the presence of conserved La motif domains that fold into RNA recognition motifs. Primarily localized in the nucleus, LARP1B functions as a positive regulator of translation by binding to specific RNA targets. It is a paralog of LARP1 and shares structural features with the La-related protein family, enabling protein-protein interactions through its conserved motifs. The gene undergoes alternative splicing to produce multiple isoforms with distinct functional properties. Clinically, LARP1B has been associated with prostate cancer, where its role in translational control may contribute to disease progression. |
检测原理