Overview
| 别名 | Spermatogenesis-associated protein 31H1 |
| 基因名 | C2orf16 |
| UniProt ID | Q68DN1 |
| 反应种属 | Human |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 7G2-B2-K8 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 224 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | IHC-1:100-1:200 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | SPATA31 subfamily H member 1 (C2orf16) is a large protein belonging to the SPATA31 subfamily, characterized by a conserved domain implicated in spermatogenesis-associated processes. It localizes to both the nucleus and extracellular exosomes, suggesting dual roles in gene regulation and intercellular signaling. The protein features potential coiled-coil regions that likely facilitate protein-protein interactions during germ cell development. While its exact enzymatic activities remain uncharacterized, its evolutionary conservation across mammals points to a fundamental role in fertility pathways. Clinically, genomic proximity and specific single-nucleotide polymorphisms link the SPATA31H1 locus to metabolic conditions, including hyperlipoproteinemia type V and markers of insulin resistance. |
检测原理