Overview
| 别名 | Putative ciliary rootlet coiled-coil protein-like 2 protein; Ciliary rootlet coiled-coil protein pseudogene 3 |
| 基因名 | CROCCP3 |
| UniProt ID | Q8IVE0 |
| 反应种属 | Human |
| 应用 | IHC-P,ELISA |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 3Q8-X8-Q5 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 33 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | IHC-1:100-1:200; ELISA-1:250-1:500 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Putative ciliary rootlet coiled-coil protein-like 2 (CROCCP3) is a pseudogene associated with the ciliary rootlet structure, which plays a crucial role in the organization and function of cilia in eukaryotic cells. It is believed to be involved in processes such as centriole cohesion and cilium assembly, contributing to the structural integrity of the cytoskeletal framework that supports ciliary function. It shares similarities with the CROCC gene, which encodes rootletin, an essential protein for maintaining centrosome cohesion during cell division. Research indicates that disruptions in related proteins can lead to developmental disorders such as microcephaly and Seckel syndrome, highlighting the importance of ciliary structures in cellular processes and human health. |
检测原理