Overview
| 别名 | Somatomedin-B and thrombospondin type-1 domain-containing protein; RPE-spondin |
| 基因名 | SBSPON |
| UniProt ID | Q8IVN8 |
| 反应种属 | Human |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 9N9-G4-A1 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 29 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | IHC-1:100-1:200 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Somatomedin B and thrombospondin type 1 domain containing (SBSPON) is a secreted extracellular matrix (ECM) protein characterized by an N-terminal somatomedin B-like domain and multiple thrombospondin type 1 repeats. Functioning as a structural constituent of the ECM, SBSPON exhibits scavenger receptor and polysaccharide binding activities, localizing primarily to collagen-containing matrices. It is broadly expressed across various tissues, including the brain, kidney, and diverse epithelial and stromal environments, suggesting a fundamental role in cell adhesion and matrix organization. By interacting with various ECM components, SBSPON helps maintain the integrity and functional architecture of the extracellular environment. Its domain structure is consistent with other proteins involved in cell-matrix interactions and signaling, supporting its role in tissue homeostasis and structural support. |
检测原理