Overview
| 别名 | RNA-binding protein 12B; RNA-binding motif protein 12B |
| 基因名 | RBM12B |
| UniProt ID | Q8IXT5 |
| 反应种属 | Human |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 2W1-V6-W2 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 118 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | RNA binding motif protein 12B (RBM12B) is a nuclear protein containing RNA recognition motif-like domains, implicated in the regulation of RNA splicing and the assembly of ribonucleoprotein complexes. It is widely expressed across tissues and has been characterized in various oncological contexts. Clinically, RBM12B is associated with neurodegenerative and neuro-ophthalmologic disorders. Genetic evidence links variants in this gene to conditions such as Boucher-Neuhauser syndrome and primary cerebellar degeneration, which present with cerebellar ataxia, chorioretinal atrophy, and hypogonadism. |
检测原理