Overview
| 别名 | Coiled-coil domain-containing protein 127 |
| 基因名 | CCDC127 |
| UniProt ID | Q96BQ5 |
| 反应种属 | Human |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 4E1-I6-T6 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 30 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Coiled-coil domain containing 127 (CCDC127) is a small mitochondrial protein that serves as a regulator of cellular stress responses and lipid metabolism. It has been identified as a suppressor of Hsp70 gene expression, suggesting a role in transcriptional regulation during periods of cellular stress. Recent functional studies indicate that CCDC127 is involved in maintaining lipid droplet homeostasis by enhancing contact sites between the mitochondria and the endoplasmic reticulum. This localization and activity link the protein to the coordination of cellular energy and lipid processing. As an evolutionarily conserved protein across vertebrates, CCDC127 appears to play a fundamental role in integrating mitochondrial function with broader metabolic and stress-response pathways within the cell. |
检测原理