Overview
| 别名 | WD repeat-containing protein 89 |
| 基因名 | WDR89 |
| UniProt ID | Q96FK6 |
| 反应种属 | Human |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG2a |
| 克隆号 | 1U6-E7-Q1 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 43 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | WD repeat domain 89 (WDR89) is a member of the WD-repeat protein family, characterized by multiple WD motifs that fold into a β-propeller scaffold to mediate protein-protein interactions. As a non-catalytic platform, WDR89 is predicted to facilitate the assembly of signaling or developmental complexes involved in cell cycle control and organelle biogenesis. Computational models suggest it plays a role in the development of the central nervous system, particularly the corpus callosum and ventricular system. Clinically, WDR89 has been associated with a rare autosomal dominant syndrome characterized by gastrointestinal polyposis, abnormal skin pigmentation, alopecia, and fingernail changes, highlighting its importance in systemic developmental pathways. |
检测原理