Overview
| 别名 | Coiled-coil domain-containing protein 43 |
| 基因名 | CCDC43 |
| UniProt ID | Q96MW1 |
| 反应种属 | Human |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 8L2-H3-F7 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 25 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Coiled-coil domain containing 43 (CCDC43) is a cytosolic protein characterized by alpha-helical coiled-coil domains, which are typical of proteins involved in structural and regulatory scaffolds. It interacts with various RNA-binding proteins, including YBX1 and HNRNPU, as well as ribosomal components like RPL27A, suggesting a role in the regulation of translation, splicing, and liquid-liquid phase separation. CCDC43 has been shown to promote cell proliferation, invasion, and epithelial-mesenchymal transition. Its upregulation is frequently observed in gastric and colorectal cancers, where it is linked to poor prognosis and tumor metastasis. |
检测原理