Overview
| 别名 | Interleukin-22; IL-22; Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL-TIF |
| 基因名 | IL22 |
| UniProt ID | Q9GZX6 |
| 反应种属 | Human |
| 应用 | WB,ELISA |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 2L4-S4-P6 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 20 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000; ELISA-1:250-1:500 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | IL-22 is a multifaceted cytokine that plays a crucial role in tissue homeostasis, inflammation, and host defense. It primarily targets non-hematopoietic cells, such as epithelial cells and fibroblasts, promoting their proliferation and survival. IL-22 functions as a double-edged sword in various diseases, exhibiting both protective and pathogenic effects depending on the context. In inflammatory conditions like psoriasis and inflammatory bowel disease, IL-22 can exacerbate inflammation and tissue damage. However, it also demonstrates protective functions in wound healing, tissue repair, and defense against certain infections. The balance between these opposing roles is influenced by factors such as the presence of other cytokines and the specific tissue environment. Due to its diverse effects, IL-22 has emerged as a potential therapeutic target for various conditions, including autoimmune diseases, infections, and tissue regeneration. |
检测原理