Overview
| 别名 | Mitochondrial fission regulator 1-like |
| 基因名 | MTFR1L |
| UniProt ID | Q9H019 |
| 反应种属 | Human |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 3W5-R2-E5 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 31 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Mitochondrial fission regulator 1 like (MTFR1L) is a protein that plays a crucial role in regulating mitochondrial morphology and dynamics. It is localized to the outer mitochondrial membrane and is involved in the adaptation of mitochondrial dynamics to metabolic changes. MTFR1L is phosphorylated by AMP-activated protein kinase (AMPK), which controls its function in regulating mitochondrial morphology, including mitochondrial fission and fusion events. Loss of MTFR1L leads to mitochondrial elongation and increased mitochondrial fusion events, suggesting its importance in maintaining mitochondrial homeostasis. While there is no direct association with specific diseases, alterations in MTFR1L expression have been observed in response to various chemical exposures, such as bisphenol A and carbon nanotubes, which may have implications for cellular health. |
检测原理