Overview
| 别名 | Haloacid dehalogenase-like hydrolase domain-containing protein 2 |
| 基因名 | HDHD2 |
| UniProt ID | Q9H0R4 |
| 反应种属 | Human |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 5I9-A3-W9 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 28 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | IHC-1:100-1:200 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Haloacid dehalogenase like hydrolase domain containing 2 (HDHD2) is a member of the HAD superfamily of hydrolases characterized by a catalytic domain that facilitates phosphatase activity and dephosphorylation. It is involved in metal ion binding and enzyme binding, with localizations observed in extracellular exosomes. HDHD2 is thought to regulate signaling pathways post-translationally, potentially interacting with partners such as HRAS and MEOX2. Clinical relevance is established through its location on chromosome 18q; its loss is associated with Chromosome 18q Deletion Syndrome. This genetic disorder is characterized by intellectual disability, growth retardation, and facial dysmorphism. |
检测原理