Overview
| 别名 | Opticin; Oculoglycan |
| 基因名 | OPTC |
| UniProt ID | Q9UBM4 |
| 反应种属 | Human,Rat |
| 应用 | WB |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG2b |
| 克隆号 | 5Y7-I6-T6 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 37 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Opticin (OPTC) is a member of the small leucine-rich repeat protein (SLRP) family, primarily expressed in the eye, particularly in the vitreous body, cornea, and retina. This protein plays a significant role in maintaining the structural integrity of the extracellular matrix and may interact with collagen fibrils to regulate their organization. The OPTC gene is located on chromosome 1q31–q32, a region associated with susceptibility to age-related macular degeneration (AMD) and other ocular diseases. Alterations in OPTC expression have been linked to primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG). |
检测原理