Overview
| 别名 | Integrin beta-1-binding protein 2; Melusin |
| 基因名 | ITGB1BP2 |
| UniProt ID | Q9UKP3 |
| 反应种属 | Human,Rat |
| 应用 | WB,IP,CHIP,ELISA |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 8B1-G8-S4 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 38 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | WB-1:1000; IP-1:100; CHIP-1:100; ELISA-1:200 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Integrin beta-1-binding protein 2 (ITGB1BP2) is a protein that interacts with integrin beta-1, playing a crucial role in cell adhesion and signaling pathways. It is involved in the regulation of integrin-mediated cellular processes, including cell migration, proliferation, and survival. By binding to integrin beta-1, ITGB1BP2 helps modulate the interaction between cells and the extracellular matrix, which is essential for maintaining tissue architecture and function. Dysregulation of ITGB1BP2 has been implicated in various diseases, particularly cancer, where altered expression can affect tumor progression and metastasis. For instance, reduced levels of ITGB1BP2 have been associated with increased invasive potential in certain cancers, suggesting its role as a tumor suppressor. Additionally, its involvement in signaling pathways linked to inflammation and immune responses may contribute to autoimmune disorders. |
检测原理