Overview
| 别名 | Napsin-A; Aspartyl protease 4; ASP4; Asp 4; Napsin-1; TA01/TA02 |
| 基因名 | NAPSIN-A |
| UniProt ID | O96009 |
| 反应种属 | Human |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 亚型 | IgG1 |
| 克隆号 | 3E2-D7-H7 |
| 克隆性 | Monoclonal Antibody |
| 分子量 | Calculated MW: 45 kDa |
| 纯化方式 | Affinity Purified |
| 产品形式 | Liquid |
| 推荐稀释比 | IHC-1:100-1:200 |
| 存储缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| 保存温度 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 背景信息 | Napsin A aspartic peptidase (NAPSIN-A) is a pepsin-family aspartic proteinase expressed predominantly in type II pneumocytes of the lung and in the kidney. Synthesized as a zymogen, it is processed into its active form, where it is thought to participate in the maturation of surfactant proteins. Napsin A is a highly specific diagnostic marker in pathology; its expression is retained in primary lung adenocarcinomas and renal cell carcinomas but is absent in most other tumor types. This specificity makes Napsin A an invaluable tool in immunohistochemistry for differentiating lung primary tumors from metastases and identifying specific renal neoplasms. |
检测原理